You know, all pickups are different. I would look to see what the Duesenbergs
can do that your other pickups can't, versus looking at it the other way around.
Like different tools for different jobs type thing. But, if you are looking to make it your #1 because of the way it feels or something, then I would get a set of pickups that are exactly tailord to what it is you are looking to do when you play. Pickups are not that expensive, especially for guys with $1500 guitars.
The GFS pups might do it for you, one way to find out. But if they don't, you will then need to go out and spend the coin to get the pickups you should have bought in the first place, and they will cost more because you lost money on the GFS pups, ..been there.
That said, pots and capacitor values can make a big difference on how pickups sound, if they are a little too dark or too bright. And switching between guitars you will sometimes have to make radical changes in your amp settings to get the goods.
Anyway, just some ideas.
Good points.....It's nice to have different guitars with different pickups (with their own strengths and weaknesses) for different voicings. You can tweak the tone of a set of pickups in a guitar like you mention too by playing with component values and pickup/pole height.
OP: what is it exactly you don't like about the distorted tone?