Despite the controversy, I think it is fair to say that ALL OTHER THINGS BEING EQUAL, you can expect a solid spruce top to be more resonant and "open sounding" than the equivalent laminate. This is of course a generalization, but I believe a reasonable one.
The solid top should also improve with age as it "opens up" to a degree greater than laminate.
I have a super cheap all mahogany laminate that sounds great and comparable to most solid topped guitars in terms of its resonance. On the other hand, my own experience (including owning a couple all laminate Yamahas) is that most laminate guitars TEND to sound a little more compressesed and "nasally" in comparison to solid topped guitars.
Again--all generalizations, but you have to start with some point of reference, right?