I won't say that the room doesn't have any effect on the sound, but in a very tight mic'd situation like micing a loud guitar amp "very" close to the grill cloth, the room wont affect the sound much. A huge majority of the sound that the mic is picking up is from the source, and very little reflection from the room. But don't be afraid to try anything, no matter how funny it seems. sometimes you accidentally come across a technique that works.