After ditching my first amp, a Gorilla, I got a Fender Princeton 65 solid state amp. I thought that it was totally amazing, and the only amp in the world that could possibly sound better was a Hiwatt Custom 50 that was at the rehearsal studio we often used. I got a second one to run stereo. Eventuly, I ditched those to play a Peavey Ranger 212 tube amp. I loved it, until it blew up. I got a Vox AC15 while still owning the Peavey, and was hooked. Once my Peavey blew up, I replaced it with an AC30. I'm good to go now!
For effects, I went through a few multi-fx units, most notably a Digitech RP-7, a Pod 2.0 with 4-button footswitch, and finally the pedalboard of stomp boxes I have now. My Green Screamer, MXR Distortion III, and Boss DD-20 are used the most, and make me a happy guitarist.